Życie czwórki pracowników uniwersytetu w Pasadenie zmienia się całkowicie, kiedy poznają Penny - zupełnie normalną dziewczynę. Od tego momentu nic już nie będzie takie jak wcześniej.
| as Leonard Hofstadter | |
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| as Sheldon Cooper | |
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| as Penny | |
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| as Howard Wolowitz | |
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| as Rajesh Koothrappali | |
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| as Bernadette Rostenkowski | |
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| as Amy Farrah Fowler |
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| as Stuart | |
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| as Priya Koothrappali | |
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| as Barry Kripke | |
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| as Leslie Winkle | |
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| as Mary Cooper |
| 2007 Season 1 |
| 2008 Season 2 |
| 2009 Season 3 |
| 2010 Season 4 |
| 2011 Season 5 |
| 2012 Season 6 |
| 2013 Season 7 |
| 2014 Season 8 |